Introduction to Masteron

Masteron, scientifically known as Drostanolone Propionate, is an anabolic androgenic steroid first brought to the market around 1970 under the trade name Masteron by Syntex. This compound, however, was originally developed in 1959 along with Oxymetholone (Anadrol), but its release followed that of Anadrol. While Masteron has been the most recognized brand name, Syntex also provided the compound under several other names.

Masteron Profile: Functional and Distinct Traits

  • Molecular Formula: C23H36O3
  • Effective Dose: 350-500 mg/week (men), 50-100 mg/week (women)
  • Active Life: 2-3 days
  • Detection Time: 3 weeks
  • Anabolic/Androgenic Ratio: 62:25

Masteron is derived from dihydrotestosterone (DHT), a structural alteration that significantly elevates its anabolic nature. This alteration protects the hormone from metabolic breakdown in skeletal muscle. Masteron is unique among anabolic steroids for its strong anti-estrogenic properties, critical in its use in treating advanced inoperable breast cancer in postmenopausal women.

Masteron’s Diverse Impact: Therapeutic to Performance Enhancement

As a therapeutic agent, Masteron enjoyed two decades of success in combating breast cancer. However, its popularity shifted to the realm of bodybuilding, where it is primarily used today. Despite the discontinuation of the original Masteron brand, this compound is still widely used in competitive bodybuilding cycles, often deemed essential for contest preparation.

Understanding Masteron: Side Effects and Administration Guidelines

Masteron is known for being one of the few anabolic steroids with strong anti-estrogenic properties. It carries no estrogenic activity and can act as an anti-estrogen in the body. This makes it effective in breast cancer treatment and popular among bodybuilders as it could negate the need for an anti-estrogen in the right cycle.

Administration of Masteron

For Medical Use:

Masteron was used in breast cancer treatment in postmenopausal women. Dosage guidelines in this context were specific to the patient’s clinical condition.

For Athletic Use:

In bodybuilding, Masteron is appreciated for its hardening effects and is often used in cutting cycles. Dosages vary based on goals and individual tolerance.

Feedback on Masteron: Efficacy and Athletic Performance

Although Masteron is not known for significant muscle mass gains, it is highly valued for strength increases and muscle definition enhancement. Its ability to promote a harder, more defined physique is highly appreciated in bodybuilding, particularly in pre-competition phases.

Effects of Masteron

The effects of Masteron are most efficiently displayed during a cutting cycle. However, for the effects to be fully appreciated, the individual needs to be extremely lean. This is due to the androgenic nature of Masteron, which is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor.

Side Effects of Masteron

Masteron’s side effect profile is generally considered tolerable. Its primary side effects include potential impacts on cholesterol levels, suppression of natural testosterone production, and virilization symptoms in women at high doses.

Masteron Administration

The standard dose for adult men typically falls in the 300-400 mg per week range. For breast cancer treatment in women, standard dosages were prescribed, although this use is now rare.


Masteron is a unique anabolic steroid, valuable in medical treatment and athletic performance enhancement. Its nuanced effects, particularly in enhancing physique and strength without substantial mass gain, make it a distinctive choice in specific contexts.